A. Published papers in impact factor journals:

1. Jureschi, M., Lupaescu, A. V., Ion, L., Petre, B. A., Drochioiu, G. Stoichiometry of heavy metal binding to peptides involved in Alzheimer’s disease: Mass spectrometric evidence. Advances in Experimental Medicine and Biology. Adv. Exp. Med. Biol., 1140, 401-415, 2019. doi: 10.1007/978-3-030-15950-4_23 Impact factor 2.126

Acknowledgment: PN-III-P4-IDPCE-2016-0376, Contract 56/2017

2. Murariu, M., Habasescu, L., Ciobanu, C.-I., Gradinaru, R. V., Pui, A., Drochioiu, G., Mangalagiu, I. Interaction of amyloid Aβ(9-16) peptide fragment with metal ions: CD, FT-IR, and fluorescence spectroscopic studies. Int. J. Pept. Res. Therap., 25(3) 897–909, 2019, DOI: 10.1007/s10989-018-9738-1 Impact factor 1.219.

Acknowledgment: PN-III-P4-IDPCE-2016-0376, Contract 56/2017 & PN-II-RU-TE-2014-4-0437.

3. Lupaescu, A. V., Petre, B. A., Ion, L., Ciobanu, C. I., Drochioiu, G. NAP neuroprotective peptide and its analogs: Simultaneously copper and iron binding and reduction. Revista de Chimie (Bucharest), 70(5) 1784-1790, 2019. Impact factor 1.605

Acknowledgment: PN-III-P4-ID-PCE-2016-0376, Contract 56/2017

4. Iacoban, C., Rîșca, I. M., Roibu, C., Todiraşcu-Ciornea, E., Necula, R., Ilieva, D., Drochioiu, G. Tarnița polluted area: Accumulation of heavy metals and nutrients from the soil by woody species. Revista de Chimie (Bucharest), 3, 753-758, 2019. Impact factor 1.605

Acknowledgment: Contract 56/2017 & PN-II-PT-PCCA-2013-4-1149 (Contract 107/2014).

5. Necula, R., Gille, E., Dirtu, A. C., Sandu, I., Gradinaru,V. R., Drochioiu, G. Heavy metal-induced cuticular alkane changes of tall fescue (Festuca arundinacea) plantlets. Revista de Chimie, 69(7), 1682-1686, 2018. Factor de impact 1,605.

Acknowledgement: UEFISCDI PN-IIIP4-ID-PCE-2016-0376, Contract 56/2017, plus UEFISCDI, PN 16-190401, PN 16-190106.

6. Lupaescu, A. V., Jureschi, M., Ciobanu, C. I., Ion, L., Zbancioc, G., Petre, B. A., Drochioiu, G. FTIR and MS evidence for heavy metal binding to anti-amyloidal NAP-like peptides. Int. J. Pept. Res. Therap., 2019, 25, 303–309; DOI: 10.1007/s10989-018-9672-2, Impact factor 1.219.

Acknowledgment: PN-III-P4-IDPCE-2016-0376, Contract 56/2017 & PN-II-RU-TE-2014-4-0920 (B.A. Petre).

7. Lupaescu, A. V., Ciobanu, C. I., Humelnicu, I., Petre, B. A., Murariu, M., Drochioiu, G. Design and synthesis of new anti-amyloid NAP-based/like peptides. Rev. Roum. Chim., 64(6), 535-546, 2019. Impact factor 0.395

Acknowledgment: PN-III-P4-ID-PCE-2016-0376, contract 56/2017)

8. Jureschi, M., Humelnicu, I., Petre, B. A., Ciobanu, C. I., Murariu, M., Drochioiu, G. Solid phase synthesis of four analogs of amyloid-(9-16) peptide: MS and FT-IR characterization. Rev. Roum. Chim., 64(5) 433-443, 2019. Impact factor 0.395

Acknowledgment: PN-III-P4-ID-PCE-2016-0376, Contract 56/2017

9. Lupaescu, A. V., Humelnicu, I., Petre, B. A., Ciobanu, C. I., Drochioiu, G. Direct evidence for binding of aluminum to NAP anti-amyloid peptide and its analogs. Eur. J. Mass Spectrom., 2019 DOI: 10.1177/1469066719877714 Impact factor 0.851

Acknowledgment: PN-III-P4-IDPCE-2016-0376, Contract 56/2017

B. Accepted papers in impact factor journals:

10. Murariu, M., Ciobanu, C. I., Habasescu, L., Jureschi, M., Drochioiu, G. Solid phase synthesis and characterization of Aβ(9-16) peptide: its interaction with some metal ions. Rev. Roum. Chim., acceptată, 26.03.2019. Impact factor 0.395.

Acknowledgment: PN-III-P4-ID-PCE-2016-0376, Contract 56/2017 plus CNCS –UEFISCDI (PN-II-RU-TE- 2014-4-0437 acknowledged by Murariu).

11. Jureschi, M., Petre, B. A., Ion, L., Ciobanu, C. I., Drochioiu, G. Synthesis of different analogs of A(9-16) peptide: Mass spectrometric evidence for heavy metal binding. Revista de Chimie (Bucharest), (9) 2019. Impact factor 1.605

Acknowledgment: PN-III-P4-IDPCE-2016-0376, Contract 56/2017

C. ISI indexed papers:

12. Ion, L., Drochioiu, G., Lupaescu, A., Jureschi, M., Petre, B. A. Amyloid-β and anti-amyloid peptides involved in Alzheimer`s disease: Interactions with metal ions. 19th International Multidisciplinary GeoConference SGEM2019, Albena, Bulgaria, 19(6.1) 515-522, 2019. ISBN 978-619-7408-88-1; ISSN 1314-2704. DOI: 10.5593/sgem2019/6.1

Acknowledgment: Contract 56/2017

13. Jureschi, M., Drochioiu, G., Lupaescu, A., Petre, B. A., Ciobanu C. Binding of heavy metal ions to amyloid-β peptides: Interactions with NAP peptides. 19th International Multidisciplinary GeoConference SGEM2019, Albena, Bulgaria, 19(6.1) 583-590, 2019. ISBN 978-619-7408-88-1; ISSN 1314-2704. DOI: 10.5593/sgem2019/6.1

Acknowledgment: Contract 56/2017

14. Drochioiu, G., Murariu, M., Jureschi, M., Lupaescu, A., Closca, M. C. Heavy metal binding to peptides at higher pH: Novel ESI-MS approach. 18th International Multidisciplinary GeoConference SGEM 2018, Albena, Bulgaria, 18(6.2) 361-368, 2018. ISSN 1314-2704. DOI: 10.5593/sgem2018/6.2

Acknowledgment: Contract 56/2017 & Contract 182PED

15. Murariu, M., Manea, M., Drochioiu, G. Heavy metal ions binding to amyloid-β peptides: biochemical and biomedical implications. 18th International Multidisciplinary GeoConference SGEM, Albena, Bulgaria, 18(6.2) 369-376, 2018. ISSN 1314-2704. DOI: 10.5593/sgem2018/6.2

Acknowledgment: Contract 56/2017 + Contract 182PED/2017

Papers under review:
16. Murariu, M., Habasescu, L., Jureschi, M., Drochioiu, G. Alanine and serine-based mutants of Aβ(1-16) peptide: pH-dependent conformational changes to metal ion binding. Int. J. Pept. Res. Therap., 2019. The title and journal could be modified as a result of the review process.

Acknowledgment: PN-III-P4-ID-PCE-2016-0376 (Contract 56/2017) & PN-III-P2-2.1-PED-2016-0869 Project (Contract 182PED/2017)

D. Oral presentations at international conferences:

1. Ion, L., Lupăescu, A., Jureschi (Iavorschi), M., Drochioiu, G. Proteomic-based approaches for the characterization of peptides associated with Alzheimer’s disease. 9th International Conference and Expo on Proteomics and Molecular Medicine, Paris, November 13-15, 2017.

2. Drochioiu, G. Metal binding to peptides and proteins at higher pH: novel ESI-MS approach. Twentieth International Conference Materials, Methods & Technologies, Elenite holiday village, 26-30 June 2018, Bulgaria.

Acknowledgment: Contract 56/2017.

E. Posters:

3. Lupaescu, A. V., Petre, B. A., Ion, L., Ciobanu, C. I., Murariu, M., Drochioiu, G. S2-P01. Synthesis and characterization of NAP-like anti-amyloid peptides. 4th International Conference on Chemical Engineering, ICCE, Iaşi, Romania, October 31- November 2, 2018.

Acknowledgment: Contract 56/2017

4. Jureschi, M., Petre, B. A., Ion, L., Ciobanu, C. I., Murariu, M., Drochioiu, G. S2-P02. New mutant truncated amyloid-β peptides: solid phase synthesis and mass spectrometric characterization. 4th International Conference on Chemical Engineering, ICCE, Iaşi, Romania, October 31- November 2, 2018.

Acknowledgment: Contract 56/2017

5, Zaharia, M., Roman, T., Pui, A., Gradinaru, R., Pintilie, O., Zbancioc, G., Drochioiu, G. O.P. Enhanced photocatalytic degradation of dinitrophenol contaminants by ferrite (ZnFe2O4) nanoparticles. Young Researchers’ International Conference on Chemistry and Chemical Engineering (YRICCCE II), Budapest, Hungary, May 03-05, 2018.

Acknowledgment: Contract 56/2017